Reversing Diabetes in Mice
Researchers have found a novel way to reverse established diabetes in mice, and in the process, unraveled an approach that could potentially be exploited to treat pre-existing diabetes in humans.
Fighting Leukemia Notch by Notch
The coming together of two proteins in a process called dimerization is a key step in causing cancerous cell replication in certain tumors in mice.
Splicing Master Switch Impairs Cell Motility and May Prevent Cancer Spread
Researchers have implicated alternative splicing in key steps in the progression of cancer.
Danger of the Double-Stranded DNA Break
Double-stranded DNA breaks block transcription along extensive regions of the same chromosome, eventually stopping the process up to thousands of bases away from the break.
Molecular Motor Spirals Hand Over Hand
Researchers show how individual molecular motor proteins walk hand over hand along the filaments that make up the structural support of a cell.
New Role for Transfer RNA
Penn researchers have found that tRNA doesn't just shuttle genetic cargo: It also helps to control programmed cell death, which eliminates damaged cells from the body.
