Penn Medicine News Blog Archive: Research

People can have a brain full of Alzheimer's disease, but not have the dementia that typically goes along with it. By the numbers, this subset of people can have many plaques and tangles in the brain, enough to qualify them for a diagnosis of Alzheimer's disease, but in reality, they...

Penn Medicine researchers are the authors of a new study, out in the May issue of the Journal of the Federation of American Societies for Experimental Biology, that examined the biology of the effects of a sneeze on the inner structures of the nose.

The Department of Pathology and Laboratory Medicine (PLM) is celebrating National Medical Laboratory Professionals Week April 22 to 28. Medical laboratory professionals are among the unsung heroes of patient care - the team behind the scenes who are “doing the best with every test.”

A diverse team of researchers from the Perelman School of Medicine at the University of Pennsylvania is in New Orleans at the American Academy of Neurology’s 64th Annual Meeting, sharing the latest data aimed at enhancing the speed of diagnosis and treatment, and ultimately helping people with neurologic conditions.

The Philadelphia Science Festival Carnival tents have all been folded and hauled away. There have already been four nights of non-stop science cafes at local watering holes. But, there are still six more days of the festival to go, and Penn Medicine faculty will be participating at events on most of those days.

It's less than a week away! The Festival, a citywide collaboration showcasing science and technology every April, will run from April 20-29. Penn students, staff, and faculty will be participating in all kinds of events throughout the entire festival.

Approximately 12 million Americans are seen in U.S. emergency departments each year for mental health-related symptoms. Of those patients, around 650,000 are evaluated for suicide attempts. For many of these people, it’s a frightening stop on the long and painful road of suffering that results from depression, anxiety, and substance...

Penn Medicine will play a starring role in the Philadelphia Science Festival again this year. The Festival is a citywide collaboration showcasing science and technology every April. This year it runs from April 20-29 -- 10 days to celebrate the region’s strengths in science and technology, bringing together more than 105 partners from academia to museums to restaurants.

In a recent Journal of Cell Biology study Erika Holzbaur, PhD, a professor of Physiology, postdoctoral researcher Sandra Maday, Ph.D., and Karen E. Wallace, all from the Perelman School of Medicine, examined autophagosomes in neurons from transgenic mice reared with florescent green biomarker. These neurons, when grown in culture, send out axon-like projections, which grew 1 mm in two days, making it easier for the team to record movies of the sacs moving along the projection. The team saw the sacs form and engulf cargo at the end of the projections farthest from the nucleus, and mature into the degradative autolysosomes as they moved toward the cell body. The autolysosomes also become increasingly acidic as they move along the axon, most likely to aid in more efficient degradation.

New research from the Perelman School of Medicine at the University of Pennsylvania indicates that modern techniques used in rhinoplasty are showing excellent improvements in patients’ quality of life and function as compared to older techniques used for the procedure.