Penn Medicine News Blog Archive: Research

Using the Penn High Performance Computing Cluster to Unravel the Spider’s Web

Golden Silk Orb Weaver L Church Flickr Creative Commons
Uncovering the genomic architecture of spider silk genes wasn’t top of mind for Benjamin Voight, PhD, when he first came to Penn a few years ago. But he and postdoctoral researcher Paul Babb are now deep into sequencing the whole genomes of two spider species: a Golden Silk Orb Weaver and Darwin's Bark Spider.

No Magic Number - Penn Medicine Researcher to Be Among Architects of New National Sleep Recommendations

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We’ve all heard it before…“sleep experts recommend you get 7 – 8 hours of sleep per night for optimal health.” But is that true for everyone? The answer is there really is no magic number. “For years, members of the sleep research and clinical community have been discussing the issue...

2014 Facts and Figures Shows Penn Medicine’s Expanding Footprint

Facts-cover-2014
In the 2014 edition of Penn Medicine’s annual Facts and Figures report, readers can find numerous achievements in research, education, and patient care from the past year. Highlights from this year’s text include Penn Medicine continuing as one of the nation’s top recipients of National Institutes of Health funding, the...

Oxygen in our Bones

Vinogradov Nature image
Working with many colleagues, a Penn team published in Nature the first application of 2PLM to directly quantify the physiological environment of blood stem cells, called haematopoietic stem cells, or HSCs.

Beyond the Ivory Tower: Penn’s Neuroscience Grad Students Reach Out During Brain Week, and Beyond

NGG KidsJudge 2013 Synpatic Land
Philadelphia is a cerebral city this spring. To start, every March, Brain Awareness Week brings together institutions worldwide to celebrate the brain.

OncoLink Celebrates 20 Years!

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Creator Joel Goldwein, MD, Honored with “Visionary Award” at Anniversary Event Before there was Yahoo or Google, there was OncoLink—one of the first web sites to provide to cancer information, or really any information, on the internet. And it started right here at Penn Medicine. Today, 20 years later, it’s...

New Art Installation Illustrates DNA Repair and Celebrates Hope for Patients and Families Carrying BRCA Mutations

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Penn Medicine's Basser Research Center for BRCA Unveils Homologous Hope Sculpture On Wednesday, the University of Pennsylvania’s Basser Research Center for BRCA hosted a special event to formally unveil “Homologous Hope,” a new sculpture suspended from the glass atrium in the Perelman Center for Advanced Medicine. The large-scale piece was...

Transcription Factors Key to Using T Cells Against Cancer, Chronic Infection

Wherry BATF spiral blog post Mar 14
Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies.

Where Do We Go From Here? Public Health and Unconventional Natural Gas Drilling

CEET Symposium flyer Feb 14
Last week the Center of Excellence in Environmental Toxicology (CEET) and the Center for Public Health Initiatives at the University of Pennsylvania co-hosted a symposium on the public health effects of natural gas drilling operations

Celebrating a Lifetime of Dual Career Success

Armstrongs Clay Clara
The five decades of research of Clara Franzini-Armstrong and Clay Armstrong, hers on electron microscopy of the inner workings of cells and his on ion channels in cell membranes, was recognized recently by their professional society -- the Society of General Physiologists – with a named lecture series.

Art Beat: Penn Medicine Researchers Launch Nationwide Contest to Spotlight Lifesaving AEDs

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The inaugural design in Amtrak's 30th Street Station in Philadelphia. To celebrate February as American Heart Month, the News Blog is highlighting some of the latest heart-centric news and stories from all areas of Penn Medicine. It’s a lifesaving device that you might walk by every day and not even...

Could Statins be Used to Fight a Deadly Viral Infection?

Hanta entry path Hannah Barbian
Two Perelman School of Medicine microbiologists may have found a way to use statins, the well-known blockbuster cholesterol-lowering drugs, to fight the hantavirus, a mysterious and lethal microorganism that appeared suddenly in the US southwest over 20 years ago

Memory May Fade with Dementia, but Artistic Abilities and Benefits Carry On

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Since it is possible for Alzheimer's patients to create art, researchers are investigating whether art therapy improves symptoms or quality of life. A new review of studies assessing art interventions from Perelman School of Medicine researchers found that art creation and appreciation activities may improve Alzheimer's disease patients' mood, activities of daily living, quality of life, and even caregiver distress.

Penn Medicine Year in Review 2013

With 2014 just around the corner, the Penn Medicine Department of Communications is taking a look back at the many highlights and achievements of our faculty, staff, and students in 2013. From landmark breakthroughs in medical research to system-wide growth, moving forward with new leadership to celebrating milestone accomplishments in...

A Day in the Life at Penn Medicine

Each autumn, the University of Pennsylvania showcases its myriad activities — scholarly and otherwise — in a photo project called A Day in the Life. One day a year, from 12:00 a.m. to 11:59 p.m., everybody at UPenn is invited to submit photographs of what they're up to at any...

Renaissance Biochemist

Dutton head shot sketch Nov 13
Les Dutton, Ph.D., will be awarded the 2013 John Scott Award next week. He will be honored with a medal, certificate, and $12,000 for his "work on the elementary processes of oxidation-reduction and the diverse biological events coupled to it." Dutton is the Eldridge Reeves Johnson Professor of Biochemistry and Biophysics, the director of the Johnson Foundation for Molecular Biophysics, a Fellow of the Royal Society, and former chair of the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania. And an accomplished artist, but more on that later.

Finding Antitumor T cells in a Patient’s Own Cancer for Personalized Therapy

Powell Clinical Cancer Research schematic Nov 13
Patients with tumors that contain increased numbers of T lymphocytes generally survive longer than those with tumors without T-cell involvement, suggesting that T cells with potent antitumor function naturally exist in cancer and control tumor progression. With the exception of melanoma, it has been difficult to identify and isolate the tumor-reactive T cells from common cancers, however, the ability to do so could be used to fight a patient’s own cancer.

Postdocs Building Community, and Experience

Postdoc Symposium poster session Nov 13
Clearly, interest in career issues for postdocs is not new, but ways to expand the postdoc experience to ready for budding careers takes constant creativity and communication. To that end, the Biomedical Postdoctoral Council at the Perelman School of Medicine, University of Pennsylvania, held its 12th annual Postdoctoral Research Symposium last week.

Cancer Hitchhikers

Simon Cancer Discovery image cancer hitchhiker no label Oct 13 take 2
With this zoomed-in view, the Abramson Family Cancer Research Institute (AFCRI) lab of Celeste Simon, PhD, and postdoctoral fellow, T.S. Karin Eisinger-Mathason PhD, report in Cancer Discovery about the potential of the collagen-modifying enzyme PLOD2 as a new therapeutic target for the treatment of metastatic undifferentiated pleomorphic sarcoma.

Inside Look: Penn’s Bridge-to-Recovery Research May Help Heal Failing Hearts

An article in the Wall Street Journal this week highlights ongoing research at Penn Medicine looking at a new way to use ventricular assist devices (VADs) for heart failure patients. This same research was also featured in the article “Rest, Recovery, Reconditioning” in a recent edition of Penn Medicine’s System...

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