Penn Medicine News Blog Archive: Infectious Disease

Another Wound Bites the Dust - All-Star Team Treats Chronic and Complex Wounds

The new Penn Center for Wound Healing and Reconstruction – to treat people dealing with unrelenting wounds – aims to simplify the process by bringing a cadre of specialists together, centering around patient needs.

Transcription Factors Key to Using T Cells Against Cancer, Chronic Infection

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Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies.

Cancer in Waiting: Latency in Viral-Based Cancer Explained

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The lab of Erle Robertson, Ph.D., professor of Microbiology, and program leader of Tumor Virology at Penn’s Abramson Cancer Center, has been studying how Kaposi’s Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer for more than a decade.

New Hope on Horizon for Hepatitis C Patients

The 3.2 million Americans with hepatitis C may get some much-needed relief through a new regimen of all oral medications that are proving to cure most disease, with fewer side-effects than the current treatment options. The new medications are being testing in clinical trials here at Penn Medicine. Hepatitis C...

Celebrating the Work of Medical Laboratory Professionals

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To show its gratitude to all laboratory professionals, the department of Pathology and Laboratory Medicine celebrated Medical Laboratory Professionals Week April 22-26, with a host of activities, such as Phillies Night, in appreciation of all the hard work and dedication of the hundreds of staff and faculty members working in more than 30 different laboratories across the Penn campus.

Defining the Traits of Transmitted HIV-1 to Make Better Vaccines

HIV Red Ribbon by Trygve.u Mar 13
Knowing the traits of HIV-1 strains capable of establishing new infections could be important for AIDS vaccine development.

So You Think You’re Exhausted? War-Weary T Cells Have Us All Beat

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This time of year has me pretty run down, with birthdays, holidays, concerts, you name it -- all manner of good and bad stress that weighs on one’s immune system. But I never knew my T cells could get exhausted, too. Two papers from the lab of E. John Wherry,...

Deadly Choices: A Penn virologist takes on the anti-vaccine movement

Exhibit A: This year’s incoming class of the Perelman School of Medicine at the University of Pennsylvania was assigned to read Deadly Choices: How the Anti-Vaccine Movement Threatens Us All, by Paul A. Offit, MD. Issued by Basic Books in 2011, the book came out this year in paperback. During...

Connecting the Dots to an AIDS-Free Generation

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This week, HIV advocates, scientists, and patients gathered at the XIX International AIDS Conference in Washington, D.C. – the first time in 22 years the meeting was held in the United States. The group’s charge: mapping out a strategy to usher in an AIDS-free generation.

Sepsis: Deceptive and Deadly

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Sepsis researcher David Gaieski, MD, an assistant professor of Emergency Medicine in the Perelman School of Medicine and clinical director in Penn’s Center for Resuscitation Science, spoke this week with several news outlets about the issues raised by the case of the 12-year-old New York City boy who died of sepsis after his infection apparently went undetected at his doctor and an emergency room. ABCNews.com explored the reasons why these infections can be so difficult to identify when they’re easiest to treat:

Pharmacists Play Key Role in Reducing Medication Errors Among Hospitalized Patients

Drugs used in hospitals are meant to save lives – to battle infections, kill cancer cells, control pain, steady uneven heart beats, and prevent blood clots from forming when patients are unable to get out of bed and move around. But despite these healing powers, medication errors are common, and the consequences can be severe. According to the Food and Drug Administration, medication errors cause at least one death every day and injure approximately 1.3 million people each year in the United States. And countless so-called "near-misses" with incorrect dosing or drug mix-ups go unreported. In response, the federal government and hospitals across the nation have made cutting medication errors a cornerstone of patient safety initiatives. Baligh Yehia, MD, MSHP, MPP, an Infectious Diseases fellow at the University of Pennsylvania’s Perelman School of Medicine, recently published a study in the journal Clinical Infectious Diseases examining the prevalence of antiretroviral medication errors among hospital patients infected with HIV. Medication errors are a risk during hospitalizations of all kinds, but HIV patients are especially vulnerable.

Among the “Unsung Heroes” of Patient Care

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The Department of Pathology and Laboratory Medicine (PLM) is celebrating National Medical Laboratory Professionals Week April 22 to 28. Medical laboratory professionals are among the unsung heroes of patient care - the team behind the scenes who are “doing the best with every test.”

Celebrating 10 Years of Collaboration in the Fight Against HIV/AIDS

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On Monday, October 10th, members of the Botswana-UPenn Partnership (BUP) will travel from Africa to join their colleagues on Penn’s campus to celebrate 10 years of medical and academic collaboration. The partnership began in 2001, when Penn Medicine sent one physician to the southern African nation. That was during the...

A Medical Translation Long in the Making: From a Millennia-Old Mutation to New Hope for Treating AIDS

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A genetic mistake that arose thousands of years ago spares rare HIV-infected individuals the ravages of AIDS. Researchers at Penn’s School of Medicine are in the midst of translating the language of ancient genetic mistakes into today’s cures.

Committing to Patient Safety

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Penn Medicine kicked off Patient Safety Awareness Week today, with a plethora of activities and training initiatives designed to get our staff members talking about and learning more about something that’s at the heart of our work here: Keeping patients safe while they’re in our hospitals.

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