Penn Medicine News Blog Archive: Immunology

Geroscience? Much More Than a Reaction to the “Silver Tsunami”

By Karen Kreeger | November 25, 2014 | Comments Geroscience The Seven Pillars of Aging

Geroscience is essentially an interdisciplinary field at the crossroads of aging and age-related diseases. Read more

Double Trouble: How Parasitic Worms Weaken Antiviral Immunity

By Karen Kreeger | September 5, 2014 | Comments Artis CM cover warhol worms Sept 14

David Artis, PhD, professor of Microbiology and his team, including first author Lisa Osborne, PhD, demonstrated that mice already infected with parasitic helminths were worse at fighting viral infection. Read more

Exploring the Human Microbiome

By John Shea | July 2, 2014 | Comments PENN-Med_SPRING_2014_F3b_LR-1

Like many people, I have gone through life without paying much attention to my gut –- except, that is, for the times my stomach gave unmistakable indications that it was upset. Most of the time, what was happening inside said stomach remained unknown. On the whole, it was out of... Read more

Lasers and Drones: June at Penn Medicine, in Photos

By Robert Press | June 30, 2014 | Comments

The University of Pennsylvania campus largely falls silent in the summer months, but Penn Medicine keeps on truckin'. In fact, the month of June featured two of my favorite photography assignments thus far: lasers and drones. I'll explain. Hang in there, we've got a slideshow at the end of the... Read more

Lab Week 2014

By Karen Kreeger | May 8, 2014 | Comments Lab Week 2014 Rock Your Pride logo

Late last month Penn Med observed Medical Laboratory Professionals Week, a time to celebrate the hard work and dedication of the 600-plus lab professionals in more than 30 laboratories across the health system.

Transcription Factors Key to Using T Cells Against Cancer, Chronic Infection

By Karen Kreeger | March 6, 2014 | Comments Wherry BATF spiral blog post Mar 14

Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies. Read more

The “Other”Circulatory System

By Karen Kreeger | January 10, 2014 | Comments Kahn JCI image graphic Jan 14

Blood is the life force of animals. But behind the more well-known system of veins, arteries, and capillaries functions the mop-up crew, the vascular network called the lymph system. Read more

The Med Days of Summer

By Karen Kreeger | August 22, 2013 | Comments PARS 1

On the Penn Med campus, mid-August marks the start of the end for many undergrads and high-school students who are wrapping up lab experiments and making presentations about their work in an array of programs designed to showcase what research is all about. Read more

Celebrating the Work of Medical Laboratory Professionals

By Karen Kreeger | April 30, 2013 | Comments Lab Week 2013 Poster Winner

To show its gratitude to all laboratory professionals, the department of Pathology and Laboratory Medicine celebrated Medical Laboratory Professionals Week April 22-26, with a host of activities, such as Phillies Night, in appreciation of all the hard work and dedication of the hundreds of staff and faculty members working in more than 30 different laboratories across the Penn campus. Read more

Penn Student Policy Group Takes Impactful, Concise Message to DC

By Steve Graff | April 12, 2013 | Comments Groupv2

Back in December, when the chatter about budget cuts to the National Institutes of Health started getting louder, Penn PhD students Michael Allegrezza and Shaun O’Brien decided it was time to join the conversation and advocate. They wanted to bring that on-the-ground scientist voice into the mix but knew it... Read more

Defining the Traits of Transmitted HIV-1 to Make Better Vaccines

By Karen Kreeger | March 29, 2013 | Comments HIV Red Ribbon by Trygve.u Mar 13

Knowing the traits of HIV-1 strains capable of establishing new infections could be important for AIDS vaccine development. Read more

So You Think You’re Exhausted? War-Weary T Cells Have Us All Beat

By Karen Kreeger | December 20, 2012 | Comments Wherry Immunity image Dec 12

This time of year has me pretty run down, with birthdays, holidays, concerts, you name it -- all manner of good and bad stress that weighs on one’s immune system. But I never knew my T cells could get exhausted, too. Two papers from the lab of E. John Wherry,... Read more

Lowering the Age of Scientific Independence

By Karen Kreeger | October 4, 2012 | Comments Sonnenberg horizontal lab 3 Sept 12

Greg Sonnenberg, PhD, research associate in the Division of Gastroenterology and the Institute for Immunology, is one of 14 early-career scientists supported this year with an NIH Director's Early Independence Award. These support exceptional early-career scientists to move directly into independent research positions by essentially omitting the traditional post-doctoral training period. Read more

Deadly Choices: A Penn virologist takes on the anti-vaccine movement

By John Shea | October 1, 2012 | Comments

Exhibit A: This year’s incoming class of the Perelman School of Medicine at the University of Pennsylvania was assigned to read Deadly Choices: How the Anti-Vaccine Movement Threatens Us All, by Paul A. Offit, MD. Issued by Basic Books in 2011, the book came out this year in paperback. During... Read more

It’s a Matter of Presentation

By Karen Kreeger | July 26, 2012 | Comments Marks Immunity blog post graph abstract AP3

A research article in a recent issue of Immunity from the lab of Mickey Marks, PhD, professor of Pathology and Laboratory Medicine, in part explains the recurrent bacterial infections in patients with a rare genetic disease called Hermansky-Pudlak Syndrome type 2. Read more

Sepsis: Deceptive and Deadly

By Holly Auer | July 20, 2012 | Comments ER_HUP_2012

Sepsis researcher David Gaieski, MD, an assistant professor of Emergency Medicine in the Perelman School of Medicine and clinical director in Penn’s Center for Resuscitation Science, spoke this week with several news outlets about the issues raised by the case of the 12-year-old New York City boy who died of sepsis after his infection apparently went undetected at his doctor and an emergency room. explored the reasons why these infections can be so difficult to identify when they’re easiest to treat: Read more

Redirecting T Cells to Fight Cancer

By Karen Kreeger | July 17, 2012 | Comments June Immunocore cell image Oct 10

Penn Medicine is building a war chest of approaches to enhance the ability of T cells to attack as many cancer types as possible. Read more

Helping Mothers Give Their Babies the Best Start in Life

By Olivia Fermano | July 3, 2012 | Comments 391px-Breastfeeding_WPA_poster

All of Society Needs to Support Breastfeeding for Everyone to Reap the Maximum Benefits Medical journals, magazines, websites… they’re all touting the same message, something nature has known all along: breastfeeding is beneficial for both babies and mothers. The message is getting through - but not always to everyone who... Read more

Penn Medicine Team Investigates Novel Immunotherapy Techniques for High Grade (Grade IV) Brain Tumors

By Kim Menard | June 5, 2012 | Comments

Neuro-oncologist researchers at Penn are investigating ways to help patients diagnosed with the most aggressive type of brain tumor, Glioblastoma Multiforme. Building on the Abramson Cancer Center's previous success with research designed to attempt to treat cancers using novel immunotherapies, and Penn's neuro-oncology expertise, researchers will be studying two different...

What’s Happening the Rest of the Week at the Philadelphia Science Festival?

By Karen Kreeger | April 24, 2012 | Comments CIMG4426

The Philadelphia Science Festival Carnival tents have all been folded and hauled away. There have already been four nights of non-stop science cafes at local watering holes. But, there are still six more days of the festival to go, and Penn Medicine faculty will be participating at events on most of those days. Read more

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