Penn Medicine News Blog Archive: Immunology

Coming Soon in Penn Medicine: Health Costs and Innovators

By John Shea | October 28, 2016 | Comments image from http://s3.amazonaws.com/hires.aviary.com/k/mr6i2hifk4wxt1dp/16102816/680ccf3a-3502-4593-b47d-0ef10d09c391.png

The villain of the piece may change from year to year or even month to month -– it may be a cancer drug that costs more than $120,000 a year, or Turing’s Daraprim, or Mylan MV’s EpiPen -– but drug companies have been excoriated in the media with increasing frequency... Read more

How Microbes are Informing the Fight Against Cancer

By Karen Kreeger | July 14, 2016 | Comments Wherry Immunity post NIAID healthy T cell

Like many therapies today, the so-called checkpoint inhibitor drugs that boost the immune system to fight cancer have an interesting back story on how they made it into the clinic. Hint: it didn’t all start in a cancer biology laboratory. A major part of the story began with microbiologists studying... Read more

Better Together: Penn Joins Unprecedented Collaboration to Tackle Cancer Immunotherapy

By Holly Auer | April 22, 2016 | Comments Parker

It had all the makings of a science-fiction blockbuster: A can’t-lose mission with high stakes, an effort to trick a devious enemy into destroying itself, the promise of gizmos like futuristic cell replicas on tiny chips, and a cast of Hollywood’s most beautiful, bold-face names – plus a killer sound... Read more

Vice President Biden Kicks off “Moonshot” Effort at Abramson Cancer Center (PHOTOS)

By Steve Graff | January 22, 2016 | Comments Biden

Days after President Obama announced the “moonshot” to find a cancer cure during his State of the Union, Vice President Biden visited Penn’s Abramson Cancer Center to kick off the national effort he said aims to “accelerate the progress already underway” – much of which is happening right here. "You're... Read more

Repairing Injured Kidneys Through Regeneration

By Karen Kreeger | January 15, 2016 | Comments Kidney

The capacity to regenerate has mythic qualities for most of us, but the human body has very little ability to regrow body parts on its own compared to say, flatworms that can regenerate a whole new self from small pieces, or some reptiles and amphibians that can regrow lost tails... Read more

What’s the Big Idea? Cancer Leaders to Talk Precision Medicine

By Steve Graff | January 6, 2016 | Comments Lab

In a few weeks, top minds in the city and state will gather to discuss one of the hottest cancer topics in healthcare: precision medicine. It’s a term many have heard, seen on a billboard, or even experienced, but what does the omnipresent buzzword really mean today—and for tomorrow? For... Read more

Looking to Ancient Symbionts for New Cancer Therapies

By Karen Kreeger | October 26, 2015 | Comments Mitochondria Courtesy NICHD

Talk about a eureka moment: Andrea Facciabene, PhD, a research assistant professor of Obstetrics and Gynecology, was taking a walk one day on the Penn campus when it hit him: What do we really need to make immunotherapy a reality for everybody? The answer, he thought, was in the mitochondria,... Read more

Translation Starts at the Bench for Penn Fellow (VIDEO)

By Karen Kreeger | October 19, 2015 | Comments Pipette Fume Hood PP 2015

For postdoctoral fellow Kristen Pauken, PhD, what “gets her up in the morning” are the cancer immunology experiments she is conducting alongside her mentor John Wherry, PhD, director of the Institute for Immunology at the Perelman School of Medicine. His lab concentrates on getting a better handle on what makes... Read more

What's Eating the Erythrocytes?

By Karen Kreeger | July 8, 2015 | Comments Red Blood Cell Andrew Mason

In the rare, life-threatening disease called paroxysmal nocturnal hemoglobinuria (PNH), patients are stricken with chronic anemia and blood clots, when the oldest part of the immune system -- known as complement -- turns against its own red blood cells, or erythrocytes. Complement is a network of more than 50 proteins... Read more

The New Avengers: Lab-Coated Heroes Honored for Behind-the-Scenes Contributions

By Karen Kreeger | May 5, 2015 | Comments Lab week 2015 logo

Late last month Penn Medicine observed the fortieth Medical Laboratory Professionals Week, a time to recognize the hard work and dedication of the 600-plus lab professionals in more than 30 laboratories across the health system. Read more

Geroscience? Much More Than a Reaction to the “Silver Tsunami”

By Karen Kreeger | November 25, 2014 | Comments Geroscience The Seven Pillars of Aging

Geroscience is essentially an interdisciplinary field at the crossroads of aging and age-related diseases. Read more

Double Trouble: How Parasitic Worms Weaken Antiviral Immunity

By Karen Kreeger | September 5, 2014 | Comments Artis CM cover warhol worms Sept 14

David Artis, PhD, professor of Microbiology and his team, including first author Lisa Osborne, PhD, demonstrated that mice already infected with parasitic helminths were worse at fighting viral infection. Read more

Exploring the Human Microbiome

By John Shea | July 2, 2014 | Comments PENN-Med_SPRING_2014_F3b_LR-1

Like many people, I have gone through life without paying much attention to my gut –- except, that is, for the times my stomach gave unmistakable indications that it was upset. Most of the time, what was happening inside said stomach remained unknown. On the whole, it was out of... Read more

Lasers and Drones: June at Penn Medicine, in Photos

By Robert Press | June 30, 2014 | Comments

The University of Pennsylvania campus largely falls silent in the summer months, but Penn Medicine keeps on truckin'. In fact, the month of June featured two of my favorite photography assignments thus far: lasers and drones. I'll explain. Hang in there, we've got a slideshow at the end of the... Read more

Lab Week 2014

By Karen Kreeger | May 8, 2014 | Comments Lab Week 2014 Rock Your Pride logo

Late last month Penn Med observed Medical Laboratory Professionals Week, a time to celebrate the hard work and dedication of the 600-plus lab professionals in more than 30 laboratories across the health system.

Transcription Factors Key to Using T Cells Against Cancer, Chronic Infection

By Karen Kreeger | March 6, 2014 | Comments Wherry BATF spiral blog post Mar 14

Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies. Read more

The “Other”Circulatory System

By Karen Kreeger | January 10, 2014 | Comments Kahn JCI image graphic Jan 14

Blood is the life force of animals. But behind the more well-known system of veins, arteries, and capillaries functions the mop-up crew, the vascular network called the lymph system. Read more

The Med Days of Summer

By Karen Kreeger | August 22, 2013 | Comments PARS 1

On the Penn Med campus, mid-August marks the start of the end for many undergrads and high-school students who are wrapping up lab experiments and making presentations about their work in an array of programs designed to showcase what research is all about. Read more

Celebrating the Work of Medical Laboratory Professionals

By Karen Kreeger | April 30, 2013 | Comments Lab Week 2013 Poster Winner

To show its gratitude to all laboratory professionals, the department of Pathology and Laboratory Medicine celebrated Medical Laboratory Professionals Week April 22-26, with a host of activities, such as Phillies Night, in appreciation of all the hard work and dedication of the hundreds of staff and faculty members working in more than 30 different laboratories across the Penn campus. Read more

Penn Student Policy Group Takes Impactful, Concise Message to DC

By Steve Graff | April 12, 2013 | Comments Groupv2

Back in December, when the chatter about budget cuts to the National Institutes of Health started getting louder, Penn PhD students Michael Allegrezza and Shaun O’Brien decided it was time to join the conversation and advocate. They wanted to bring that on-the-ground scientist voice into the mix but knew it... Read more

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