Over the past 20 years, advancements in research and the understanding of genetics have created a boom in patient demand for genetic tests. According to the National Library of Medicine, less than 300 genetic tests were available in the 1990s; in contrast, at the end of 2012, almost 3,000 genetic... Read more
Did you know that psoriasis is more than merely a skin condition? It's a chronic inflammatory disease that increases a patient’s risk for other systemic disorders, such as atherosclerosis and renal damage. In the last year alone, researchers at the Perelman School of Medicine at the University of Pennsylvania have... Read more
WHYY’s Radio Times’ show last Friday focused on much of the progress that’s been made in the world of HIV/AIDS research and care, but there was one terrible set back that had to be addressed. Earlier that morning, news broke that the Malaysia Airlines plane struck down over the Ukraine... Read more
Late last month Penn Med observed Medical Laboratory Professionals Week, a time to celebrate the hard work and dedication of the 600-plus lab professionals in more than 30 laboratories across the health system.
Cancer Researchers and Celebrities Come Together for a Stand Up to Cancer Event to Announce New “Dream Team” “It can run, but it can’t hide.” That’s the message Robert Vonderheide, MD, DPhil, the Hanna Wise Professor in Cancer Research in the Abramson Cancer Center (ACC) and the Perelman School of... Read more
In the 19th Century, rigorous work was thought to negatively affect female fertility. It was also thought to create a masculine and angular appearance in women, thus stunting the development of femininity. These are just a sample of some of the startling yet fascinating “facts” presented by ten distinguished speakers... Read more
Working with many colleagues, a Penn team published in Nature the first application of 2PLM to directly quantify the physiological environment of blood stem cells, called haematopoietic stem cells, or HSCs. Read more
Rare Disease Day is an annual event to raise awareness with the general public and decision-makers about rare diseases and their impact on patients’ lives. Read more
Blood is the life force of animals. But behind the more well-known system of veins, arteries, and capillaries functions the mop-up crew, the vascular network called the lymph system. Read more
With 2014 just around the corner, the Penn Medicine Department of Communications is taking a look back at the many highlights and achievements of our faculty, staff, and students in 2013. From landmark breakthroughs in medical research to system-wide growth, moving forward with new leadership to celebrating milestone accomplishments in...
Patients with tumors that contain increased numbers of T lymphocytes generally survive longer than those with tumors without T-cell involvement, suggesting that T cells with potent antitumor function naturally exist in cancer and control tumor progression. With the exception of melanoma, it has been difficult to identify and isolate the tumor-reactive T cells from common cancers, however, the ability to do so could be used to fight a patient’s own cancer. Read more
An article in the Wall Street Journal this week highlights ongoing research at Penn Medicine looking at a new way to use ventricular assist devices (VADs) for heart failure patients. This same research was also featured in the article “Rest, Recovery, Reconditioning” in a recent edition of Penn Medicine’s System... Read more
Angelina Jolie’s Cancer Prevention Surgery Puts Basser Research Center for BRCA In National SpotlightBy Holly Auer | May 15, 2013 | Comments
Basser.graphic.blue.background.expanded This week, when Oscar-winning actress and humanitarian Angelina Jolie revealed that she underwent surgery to remove her breasts after learning that she carries one of the BRCA gene mutations that put her at high risk of developing breast and ovarian cancer, the news hit home here at the University of Pennsylvania. Just a year ago, Penn announced the creation of the Basser Research Center for BRCA, which was made possible by a $25 million gift from Penn alums Mindy and Jon Gray, in honor of Mindy Gray’s sister, Faith Basser, who died of ovarian cancer at age 44. As the only center in the United States devoted solely to research on prevention and treatment for cancers related to BRCA mutations, Jolie’s story turned a spotlight on the important work in progress there, and the experiences of the many other families with similar cancer risks. Read more
To show its gratitude to all laboratory professionals, the department of Pathology and Laboratory Medicine celebrated Medical Laboratory Professionals Week April 22-26, with a host of activities, such as Phillies Night, in appreciation of all the hard work and dedication of the hundreds of staff and faculty members working in more than 30 different laboratories across the Penn campus. Read more
“We Found a Change In Your DNA And We Don’t Know What it Means” – Questions and Challenges in the Era of Massively Parallel Gene SequencingBy Holly Auer | April 15, 2013 | Comments
Women who develop breast cancer while they’re young are often searching for answers about the cause for their disease or what they can do to improve their chances of being cured. While an increasing number of large genetic testing panels promise to scrutinize their DNA to uncover clues, a team of researchers from the Perelman School of Medicine and the Abramson Cancer Center has found that those powerful tests tend to produce more questions than they answer. Read more
Cover image via TIME.com This week’s TIME magazine makes an eye-catching, bold proclamation. HOW TO CURE CANCER, the cover reads, with a subhead previewing the story contained inside: “Yes, it’s now possible – thanks to new cancer dream teams that are delivering better results faster.” Much of that team science... Read more
When most people think about ways to improve their heart health, they consider eating a healthier diet, getting some additional exercise, and possibly sipping a glass of red wine each night. But few people really consider the complex role that sleep – yes, sleep – plays in their overall cardiovascular... Read more
Depression is one of the most common types of mental illness. Estimated to affect over 17 million people in the United States, it can afflict anyone at any time. Patients commonly report feelings of sadness, fear, hopelessness, and worthlessness, even if everything else in their lives seems to be going... Read more
To celebrate February as American Heart Month, the News Blog is highlighting some of the latest heart-centric news and stories from all areas of Penn Medicine. “I know this sounds like a cliché, but one of the main reasons I’m interested in learning about the genetic basis of heart... Read more
Penn Medicine is the first in the region to begin testing a new procedure to help people whose high blood pressure can't be controlled using currently available medications.