Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies.
The five decades of research of Clara Franzini-Armstrong and Clay Armstrong, hers on electron microscopy of the inner workings of cells and his on ion channels in cell membranes, was recognized recently by their professional society -- the Society of General Physiologists – with a named lecture series.
With 2014 just around the corner, the Penn Medicine Department of Communications is taking a look back at the many highlights and achievements of our faculty, staff, and students in 2013. From landmark breakthroughs in medical research to system-wide growth, moving forward with new leadership to celebrating milestone accomplishments in...
Each autumn, the University of Pennsylvania showcases its myriad activities — scholarly and otherwise — in a photo project called A Day in the Life. One day a year, from 12:00 a.m. to 11:59 p.m., everybody at UPenn is invited to submit photographs of what they're up to at any...
Les Dutton, Ph.D., will be awarded the 2013 John Scott Award next week. He will be honored with a medal, certificate, and $12,000 for his "work on the elementary processes of oxidation-reduction and the diverse biological events coupled to it." Dutton is the Eldridge Reeves Johnson Professor of Biochemistry and Biophysics, the director of the Johnson Foundation for Molecular Biophysics, a Fellow of the Royal Society, and former chair of the Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania. And an accomplished artist, but more on that later.
Patients with tumors that contain increased numbers of T lymphocytes generally survive longer than those with tumors without T-cell involvement, suggesting that T cells with potent antitumor function naturally exist in cancer and control tumor progression. With the exception of melanoma, it has been difficult to identify and isolate the tumor-reactive T cells from common cancers, however, the ability to do so could be used to fight a patient’s own cancer.
Clearly, interest in career issues for postdocs is not new, but ways to expand the postdoc experience to ready for budding careers takes constant creativity and communication. To that end, the Biomedical Postdoctoral Council at the Perelman School of Medicine, University of Pennsylvania, held its 12th annual Postdoctoral Research Symposium last week.
With this zoomed-in view, the Abramson Family Cancer Research Institute (AFCRI) lab of Celeste Simon, PhD, and postdoctoral fellow, T.S. Karin Eisinger-Mathason PhD, report in Cancer Discovery about the potential of the collagen-modifying enzyme PLOD2 as a new therapeutic target for the treatment of metastatic undifferentiated pleomorphic sarcoma.
Following a briefing on the current state of neuroscience research across the United States, held in Philadelphia's University City Science Center and hosted by Congressman Chaka Fattah, we had the opportunity to take the morning's featured speaker, Dr. Philip Rubin, Principal Assistant Director for Science at The White House Office of Science and Technology Policy (OSTP), on a whirlwind tour of brain-related research here at Penn Medicine.
In an online video series, Florie Charles, a doctoral student at the University of California at San Francisco, and founder of Youreka Science, simply uses a white board and colored markers (and occasionally a small cut out mouse -- animal, not computer peripheral) to explain findings from recent papers in an accessible, fresh, and engaging way. One of her newest videos happens to feature a recent publication from the lab of Garret FitzGerald, MD, FRS, director of Penn Medicine's Institute of Translational Medicine and Therapeutics.