A new study is shedding light on how cells respond to surrounding “stiff” tissue that can influence cells to go rogue—and ultimately cause disease. A better understanding of that process could help advance the development of treatments for cancers and cardiovascular disease resistant to therapy. An article in Science Signaling... Read more
Like many people, I have gone through life without paying much attention to my gut –- except, that is, for the times my stomach gave unmistakable indications that it was upset. Most of the time, what was happening inside said stomach remained unknown. On the whole, it was out of... Read more
The lab of Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology, and colleagues, recently showed in a Cancer Cell study that some tumor components, particularly fibroblasts, constrain tumor growth. Read more
As the Perelman School of Medicine fast approaches its 250th birthday (to be celebrated next May), I’ve found it fascinating to look at how the school has changed -- and sometimes how its leaders have seemed to anticipate what lay ahead. Last month, the medical campus was visited by some... Read more
It’s only been a little over two weeks since the end of the 2014 Philadelphia Science Festival, but the inspiration, as well as love and knowledge of science that Penn Medicine faculty, staff, and students shared with members of the public, will last far into the next year.
The first annual Million Dollar Bike Ride is finally here. On Saturday, May 3, 2014, close to 500 riders and many other volunteers and family members will gather at Highline Park on Penn’s campus to raise funds for and awareness about rare diseases. Read more
Sleep -- elusive to some, mysterious to all -- is the topic of a special event at Franklin Institute’s Fels Planetarium on Wednesday, April 30, at 6:30 p.m. called Sleep: A Bedtime Story, part of the signature programs on the 2014 Philadelphia Science Festival schedule.
Head outdoors this weekend with Penn Medicine to kick off the fourth annual Philadelphia Science Festival.The weather for Saturday and Sunday is predicted to be 0% showers, with highs in the upper 60s and low 70s. Join Penn Medicine faculty, students, and staff at two of the city’s most spectacular...
Uncovering the genomic architecture of spider silk genes wasn’t top of mind for Benjamin Voight, PhD, when he first came to Penn a few years ago. But he and postdoctoral researcher Paul Babb are now deep into sequencing the whole genomes of two spider species: a Golden Silk Orb Weaver and Darwin's Bark Spider. Read more
PSF 2011 Carnival Dry icePenn Medicine will again play a starring role in the 4th annual Philadelphia Science Festival, a citywide collaboration showcasing science and technology every spring. Read more
In the mid-1990s, scientists for the first time were able to isolate and clone the BRCA1 and BRCA2 genes, mutations in which were thought to increase susceptibility to early onset breast and ovarian cancers. A new Perspective published last week in Science takes a look back at the last twenty... Read more
Working with many colleagues, a Penn team published in Nature the first application of 2PLM to directly quantify the physiological environment of blood stem cells, called haematopoietic stem cells, or HSCs. Read more
Philadelphia is a cerebral city this spring. To start, every March, Brain Awareness Week brings together institutions worldwide to celebrate the brain. Read more
Business is brisk in the lab of John Wherry and his team from the Department of Microbiology and the Institute for Immunology for papers on killer and helper T cells. Two studies -- bound by their focus on transcription factors important in the immune response – have come out of the lab in the last few weeks. And, they both identify potential new targets for cancer immunotherapies. Read more
Rare Disease Day is an annual event to raise awareness with the general public and decision-makers about rare diseases and their impact on patients’ lives. Read more
Last week the Center of Excellence in Environmental Toxicology (CEET) and the Center for Public Health Initiatives at the University of Pennsylvania co-hosted a symposium on the public health effects of natural gas drilling operations Read more
The five decades of research of Clara Franzini-Armstrong and Clay Armstrong, hers on electron microscopy of the inner workings of cells and his on ion channels in cell membranes, was recognized recently by their professional society -- the Society of General Physiologists – with a named lecture series. Read more
The lab of Erle Robertson, Ph.D., professor of Microbiology, and program leader of Tumor Virology at Penn’s Abramson Cancer Center, has been studying how Kaposi’s Sarcoma-associated Herpes Virus (KSHV) subverts normal cell machinery to cause cancer for more than a decade. Read more
Two Perelman School of Medicine microbiologists may have found a way to use statins, the well-known blockbuster cholesterol-lowering drugs, to fight the hantavirus, a mysterious and lethal microorganism that appeared suddenly in the US southwest over 20 years ago Read more
Blood is the life force of animals. But behind the more well-known system of veins, arteries, and capillaries functions the mop-up crew, the vascular network called the lymph system. Read more